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THBS2 (基因名), Thrombospondin-2 (蛋白名), tsp2_human.
产品名称:

Human THBS2/ Thrombospondin-2 Recombinant Protein
凝血栓蛋白

货号:

R1899h

商标:
EIAab®
监管等级:
别名:

TSP2

序列号:
P35442
来源:
E.coli
种属:
Human
标签:
His
序列:
960-1172aa
预估分子量:
23.43 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human THBS2 Protein
规格 & 价格: cart
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Human THBS2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human THBS2 Protein
Recombinant human THBS2 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 6q27 by HGNC 6q27 by Entrez Gene 6q27 by Ensembl
THBS2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homotrimer; disulfide-linked. Interacts (via the TSP type I repeats) with CD36; the interaction conveys an antiangiogenic effect. Interacts (via the TSP type I repeats) with HRG; the interaction blocks the antiangiogenic effect of THBS2 with CD36 (By similarity). Can bind to fibrinogen, fibronectin, laminin and type V collagen.


功能:
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。

[1].
"A functional polymorphism in THBS2 that affects alternative splicing and MMP binding is associated with lumbar-disc herniation."

[2].
"Decreased frequency of the 3'UTR T>G single nucleotide polymorphism of thrombospondin-2 gene in sudden death due to plaque erosion."

[3].
"Polymorphisms in thrombospondin genes and myocardial infarction: a case-control study and a meta-analysis of available evidence."

[4].
"Assessment of genetic risk factors for thoracic aortic aneurysm in hypertensive patients."

[5].
"Association of common promoter polymorphisms of MCP1 with hepatitis B virus clearance."

[6].
"Structure of the calcium-rich signature domain of human thrombospondin-2."

[7].
"Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes."

[8].
"Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction."

[9].
"Disulfide connectivity of recombinant C-terminal region of human thrombospondin 2."

[10].
"Sequence and characterization of the complete human thrombospondin 2 cDNA: potential regulatory role for the 3' untranslated region."
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