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DCT (基因名), L-dopachrome tautomerase (蛋白名), tyrp2_human.
产品名称:

Human DCT/ L-dopachrome tautomerase Recombinant Protein
L-多巴色素异构酶DCT

货号:

R1154h

商标:
EIAab®
监管等级:
别名:

L-dopachrome Delta-isomerase, Tyrosinase-related protein 2, TRP-2, DCT, TYRP2

序列号:
P40126
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human DCT Protein
规格 & 价格: cart
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Human DCT Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 13q32.1 by HGNC 13q32.1 by Entrez Gene 13q32.1 by Ensembl
DCT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Tyrosinase, TYRP1 and DCT/TYRP2 may form a multienzyme complex.


功能:
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA) (PubMed:8306979). Involved in regulating eumelanin and phaeomelanin levels.


亚细胞位置:
Melanosome membrane Single-pass type I membrane protein Melanosome Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38.


该产品尚未在任何出版物中被引用。

[1].
"Molecular characterization of a human tyrosinase-related-protein-2 cDNA. Patterns of expression in melanocytic cells."

[2].
"Pre-existing immunity to tyrosinase-related protein (TRP)-2, a new TRP-2 isoform, and the NY-ESO-1 melanoma antigen in a patient with a dramatic response to immunotherapy."

[3].
"Chromosomal structure of the human TYRP1 and TYRP2 loci and comparison of the tyrosinase-related protein gene family."

[4].
"Cloning of the human DOPAchrome tautomerase/tyrosinase-related protein 2 gene and identification of two regulatory regions required for its pigment cell-specific expression."

[5].
"Molecular cloning and functional analysis of a cDNA coding for human DOPAchrome tautomerase/tyrosinase-related protein-2."

[6].
"Sequence of the human dopachrome tautomerase-encoding TRP-2 cDNA."

[7].
"[Association study of Trp2 allele polymorphism with degenerative disc disease in a Chinese Han nationality]."

[8].
"Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers."

[9].
"Absence of tyrosinase-related protein-2/dopachrome tautomerase transcripts in PBMCs from vitiligo patients."

[10].
"TRP-2 expression protects HEK cells from dopamine- and hydroquinone-induced toxicity."
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