首页 > 重组蛋白 > Human SLC14A1 Recombinant Protein

SLC14A1 (基因名), Urea transporter 1 (蛋白名), ut1_human.

产品名称:

Human SLC14A1/ Urea transporter 1 Recombinant Protein
尿素通道蛋白1

货号:

R12521h

商标:

EIAab^®

监管等级:

RUO

别名:

Solute carrier family 14 member 1, Urea transporter, erythrocyte, HUT11, JK, RACH1, UT1, UTE

序列号:

Q13336

来源:

E.coli

种属:

Human

标签:

His

序列:

1-240aa

预估分子量:

26.4 kDa (monomer)

纯度:

Greater than 90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

规格 & 价格:

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Human SLC14A1 Protein

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

基因位点

Cytogenetic band: 18q12.3 by HGNC 18q12.3 by Entrez Gene 18q12.3 by Ensembl

SLC14A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Homotrimer; each subunit contains a pore through which urea permeates. Identified in a complex with STOM.

功能:

Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.

亚细胞位置:

Cell membrane Multi-pass membrane protein Basolateral cell membrane Multi-pass membrane protein Restricted to the basolateral membrane in various portions of the urothelium.

数据库链接

UniGene:

Hs.101307

SMR:

Q13336

STRING:

9606.ENSP00000390637

KEGG:

hsa:6563

MIM:

111000

Pfam:

PF03253

Uniprot:

Q13336

相关产品

Mouse Slc14a1 ELISA Kit

Rat Slc14a1 ELISA Kit

Bovine SLC14A1 ELISA Kit

Mouse Slc14a1 CLIA Kit

Rat Slc14a1 CLIA Kit

序列长度:

389

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

150:

200:

250:

300:

350:

389:

IMTTKNSNIY | KMPLSKVTYP | EENRIFYLQA | KKRMVESPL

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"Kidd blood group and urea transport function of human erythrocytes are carried by the same protein."

(PMID: 7797558)

[2].

"Genomic characterization of the kidd blood group gene:different molecular basis of the Jk(a-b-) phenotype in Polynesians and Finns."

(PMID: 10644814)

[3].

"At physiological expression levels the Kidd blood group/urea transporter protein is not a water channel."

(PMID: 10514515)

[4].

"European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene."

(PMID: 21750109)

[5].

"A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3."

(PMID: 21824976)

[6].

"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

(PMID: 20379614)

[7].

"L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms."

(PMID: 20424473)

[8].

"Introduction of a real-time-based blood-group genotyping approach."

(PMID: 18510579)

[9].

"Erythroid urea transporter deficiency due to novel JKnull alleles."

(PMID: 18028269)

[10].

"ABO, Rh, MNS, Duffy, Kidd,Yt, Scianna, and Colton blood group systems in indigenous Chinese."

(PMID: 15783300)

[1].

人尿素通道蛋白1(SLC14A1)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人尿素通道蛋白1(SLC14A1)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人尿素通道蛋白1(SLC14A1)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人尿素通道蛋白1(SLC14A1)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人尿素通道蛋白1(SLC14A1)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人尿素通道蛋白1(SLC14A1)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人尿素通道蛋白1(SLC14A1)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人尿素通道蛋白1(SLC14A1)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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