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VDAC1 (基因名), Voltage-dependent anion-selective channel protein 1 (蛋白名), vdac1_pig.
产品名称:

Pig VDAC1/ Voltage-dependent anion-selective channel protein 1 Recombinant Protein
电压依赖性阴离子选择性通道蛋白1

货号:

R12942p

商标:
EIAab®
监管等级:
别名:

VDAC-1

序列号:
Q9MZ16
来源:
E.coli
种属:
Pig
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Pig VDAC1 Protein
规格 & 价格: cart
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts with hexokinases including HK1. The HK1-VDAC1 complex interacts with ATF2. Interacts with BCL2L1. Interacts with BAK1. Interacts with BOP/C22orf29 (via BH3 domain). Interacts with beta amyloid and APP; induces VDAC1 dephosphorylation.


功能:
Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.


亚细胞位置:
Mitochondrion outer membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein Membrane raft Multi-pass membrane protein


该产品尚未在任何出版物中被引用。
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