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VEGFD (基因名), Vascular endothelial growth factor D (蛋白名), vegfd_human.
产品名称:

Human VEGFD/ Vascular endothelial growth factor D Recombinant Protein
血管内皮细胞生长因子D

货号:

R0146h

商标:
EIAab®
监管等级:
别名:

c-Fos-induced growth factor, FIGF, VEGF-D, FIGF

序列号:
O43915
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human VEGFD Protein
规格 & 价格: cart
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Human VEGFD Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: Xp22.2 by HGNC Xp22.2 by Entrez Gene Xp22.2 by Ensembl
VEGFD Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer; non-covalent and antiparallel.


功能:
Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"Human FIGF: cloning, gene structure, and mapping to chromosome Xp22.1 between the PIGA and the GRPR genes."

[2].
"Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers."

[3].
"Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)."

[4].
"Molecular cloning of a novel vascular endothelial growth factor, VEGF-D."

[5].
"[Expression of VEGF-C and VEGF-D in gastric carcinoma and its relationship with lymph node metastases]."

[6].
"[Expressions of VEGF-C and VEGF-D and their correlation with lymphangiogenesis and angiogenesis in gallbladder carcinoma]."

[7].
"Vascular endothelial growth factor D and intratumoral lymphatics as independent prognostic factors in epithelial ovarian carcinoma."

[8].
"[Relationship between clinicopathologic characteristics and expression of VEGF-C and VEGF-D in esophageal squamous cancer]."

[9].
"Vascular endothelial growth factor-D is correlated with hepatic metastasis from gastric cancer after radical gastrectomy."

[10].
"Lymphangiogenesis induced by VEGF-C and VEGF-D promotes metastasis and a poor outcome in breast carcinoma: a retrospective study of 61 cases."
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