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WASF3 (基因名), Wiskott-Aldrich syndrome protein family member 3 (蛋白名), wasf3_human.
产品名称:

Human WASF3/ Wiskott-Aldrich syndrome protein family member 3 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Protein WAVE-3, Verprolin homology domain-containing protein 3, WASP family protein member 3, KIAA0900, SCAR3, WAVE3

序列号:
Q9UPY6
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human WASF3 Protein
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Human WASF3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 13q12.13 by HGNC 13q12.13 by Entrez Gene 13q12.13 by Ensembl
WASF3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Binds actin and the Arp2/3 complex.


功能:
Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.


亚细胞位置:
Cytoplasm Cytoskeleton


该产品尚未在任何出版物中被引用。

[1].
"Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex."

[2].
"Genomic organization and expression profile of the human and mouse WAVE gene family."

[3].
"Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration."

[4].
"WAVE3 is associated with invasiveness in prostate cancer cells."

[5].
"c-Abl-mediated phosphorylation of WAVE3 is required for lamellipodia formation and cell migration."

[6].
"WAVE3 promotes cell motility and invasion through the regulation of MMP-1, MMP-3, and MMP-9 expression."

[7].
"The DNA sequence and analysis of human chromosome 13."

[8].
"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."

[9].
"WAVE3, an actin-polymerization gene, is truncated and inactivated as a result of a constitutional t(1;13)(q21;q12) chromosome translocation in a patient with ganglioneuroblastoma."

[10].
"Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
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