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WASL (基因名), Neural Wiskott-Aldrich syndrome protein (蛋白名), wasl_bovin.
产品名称:

Bovine WASL/ Neural Wiskott-Aldrich syndrome protein Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

N-WASP

序列号:
Q95107
来源:
E.coli
种属:
Bovine
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Bovine WASL Protein
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Bovine WASL Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Binds actin and the Arp2/3 complex. Interacts with CDC42. Binds to SH3 domains of GRB2. Interacts with the C-terminal SH3 domain of DNMBP. Interacts with the WW domains of PRPF40A/FBP11. Interacts with NOSTRIN. Binds to TNK2. Interacts with PTK2/FAK1. Interacts with PACSIN1, PACSIN2 and PACSIN3. Interacts with SNX33 (By similarity). Interacts with SNX9.


功能:
Involved in mitosis and cytokinesis, via its role in the regulation of actin polymerization (By similarity). Regulates actin polymerization by stimulating the actin-nucleating activity of the actin-related protein 2/3 (Arp2/3) complex. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression. Plays a role in dendrite spine morphogenesis.


亚细胞位置:
Nucleus Cytoplasm Cytoplasm Cytoskeleton Preferentially localized in the cytoplasm when phosphorylated and in the nucleus when unphosphorylated. Exported from the nucleus by an nuclear export signal (NES)-dependent mechanism to the cytoplasm.


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