首页 > 重组蛋白 > Human WDR1 Recombinant Protein

WDR1 (基因名), WD repeat-containing protein 1 (蛋白名), wdr1_human.

产品名称:

Human WDR1/ WD repeat-containing protein 1 Recombinant Protein

货号:

R14349h

商标:

EIAab^®

监管等级:

RUO

别名:

Actin-interacting protein 1, NORI-1, AIP1

序列号:

O75083

来源:

E.coli

种属:

Human

标签:

His

纯度:

>90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

规格 & 价格:

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Human WDR1 Protein

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

基因位点

Cytogenetic band: 4p16.1 by HGNC 4p16.1 by Entrez Gene 4p16.1 by Ensembl

WDR1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

N/A

功能:

Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (PubMed:15629458). Enhances cofilin-mediated actin severing (By similarity). Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions (PubMed:18494608). Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance (By similarity). Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape changes during PCP; the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension (By similarity). Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt (PubMed:25792565).

亚细胞位置:

Cytoplasm Cytoskeleton Cell projection Podosome Cell junction

数据库链接

UniGene:

Hs.128548

SMR:

O75083

STRING:

9606.ENSP00000427687

KEGG:

hsa:9948

MIM:

604734

Pfam:

PF00400

Uniprot:

O75083

相关产品

Mouse Wdr1 ELISA Kit

Rat Wdr1 ELISA Kit

Bovine WDR1 ELISA Kit

Chicken WDR1 ELISA Kit

Mouse Wdr1 CLIA Kit

序列长度:

606

序列:

仅供参考，详细请咨询（services@eiaab.com）

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606:

EWTITY

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"Critical roles of actin-interacting protein 1 in cytokinesis and chemotactic migration of mammalian cells."

(PMID: 18494608)

[2].

"AIP1/WDR1 supports mitotic cell rounding."

(PMID: 15629458)

[3].

"A gene upregulated in the acoustically damaged chick basilar papilla encodes a novel WD40 repeat protein."

(PMID: 10036186)

[4].

"Actin-interacting protein 1 controls assembly and permeability of intestinal epithelial apical junctions."

(PMID: 25792565)

[5].

"Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia."

(PMID: 18179892)

[6].

"Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization."

(PMID: 17293856)

[7].

"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."

(PMID: 15592455)

[8].

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

(PMID: 15489334)

[9].

"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."

(PMID: 12665801)

[10].

"Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis."

(PMID: 30575818)

[1].

人WDR1重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人WDR1重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人WDR1重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人WDR1重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人WDR1重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人WDR1重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人WDR1重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人WDR1重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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