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WNT6 (基因名), Protein Wnt-6 (蛋白名), wnt6_human.
产品名称:

Human WNT6/ Protein Wnt-6 Recombinant Protein
蛋白质Wnt-6

货号:

R12696h

商标:
EIAab®
监管等级:
序列号:
Q9Y6F9
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human WNT6 Protein
规格 & 价格: cart
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Human WNT6 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 2q35 by HGNC 2q35 by Entrez Gene 2q35 by Ensembl
WNT6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with PORCN.


功能:
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway.


亚细胞位置:
Secreted Extracellular space Extracellular matrix


该产品尚未在任何出版物中被引用。

[1].
"WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells."

[2].
"Partial cloning and assignment of WNT6 to human chromosome band 2q35 by in situ hybridization."

[3].
"WNT6 is a novel target gene of caveolin-1 promoting chemoresistance to epirubicin in human gastric cancer cells."

[4].
"Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia."

[5].
"Analysis of candidate genes on chromosome 2 in oral cleft case-parent trios from three populations."

[6].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[7].
"Overexpressed PLAGL2 transcriptionally activates Wnt6 and promotes cancer development in colorectal cancer."

[8].
"WNT6 is an effective marker for osteosarcoma diagnosis and prognosis."

[9].
"Novel missense mutation in WNT6 in 100 couples with unexplained recurrent miscarriage."

[10].
"PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion."
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