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ZEB2 (基因名), Zinc finger E-box-binding homeobox 2 (蛋白名), zeb2_human.
产品名称:

Human ZEB2/ Zinc finger E-box-binding homeobox 2 Recombinant Protein
ZEB2

货号:

R14971h

商标:
EIAab®
监管等级:
别名:

Smad-interacting protein 1, Zinc finger homeobox protein 1b, SMADIP1, HRIHFB2411, KIAA0569, SIP1, ZFHX1B, ZFX1B

序列号:
O60315
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ZEB2 Protein
规格 & 价格: cart
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Human ZEB2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 2q22.3 by HGNC 2q22.3 by Entrez Gene 2q22.3 by Ensembl
ZEB2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Binds activated SMAD1, activated SMAD2 and activated SMAD3; binding with SMAD4 is not detected (By similarity). Interacts with CBX4 and CTBP1.


功能:
Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。

[1].
"A missense mutation in the ZFHX1B gene associated with an atypical Mowat-Wilson syndrome phenotype."

[2].
"Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin."

[3].
"Ocular coloboma and high myopia with Hirschsprung disease associated with a novel ZFHX1B missense mutation and trisomy 21."

[4].
"Mutations in SIP1, encoding Smad interacting protein-1, cause a form of Hirschsprung disease."

[5].
"Loss-of-function mutations in SIP1 Smad interacting protein 1 result in a syndromic Hirschsprung disease."
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