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ZMIZ1 (基因名), Zinc finger MIZ domain-containing protein 1 (蛋白名), zmiz1_human.
产品名称:

Human ZMIZ1/ Zinc finger MIZ domain-containing protein 1 Recombinant Protein

货号:

R2955h

商标:
EIAab®
监管等级:
别名:

PIAS-like protein Zimp10, Retinoic acid-induced protein 17, KIAA1224, RAI17, ZIMP10

序列号:
Q9ULJ6
来源:
E.coli
种属:
Human
标签:
His
序列:
1-120aa
预估分子量:
13.2 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ZMIZ1 Protein
规格 & 价格: cart
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Human ZMIZ1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human ZMIZ1 Protein
Recombinant human ZMIZ1 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 10q22.3 by HGNC 10q22.3 by Entrez Gene 10q22.3 by Ensembl
ZMIZ1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with AR, but not with ESR1, NR3C1, PGR, THRB nor VDR. Interacts with NOTCH1 and RBPJ (PubMed:14609956, PubMed:26522984). Interacts with SMARCA4.


功能:
Acts as transcriptional coactivator. Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation (PubMed:14609956, PubMed:26522984). Involved in transcriptional activation of a subset of NOTCH1 target genes including MYC. Involved in thymocyte and T cell development.


亚细胞位置:
Nucleus speckle Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia."

[2].
"Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci."

[3].
"Multiple common variants for celiac disease influencing immune gene expression."

[4].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[5].
"Association between genome-wide association studies reported SNPs and pediatric-onset Crohn's disease in Canadian children."
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