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SLC30A8 (基因名), Zinc transporter 8 (蛋白名), znt8_human.
产品名称:

Human SLC30A8/ Zinc transporter 8 Recombinant Protein
锌转运体8

货号:

R0319h

商标:
EIAab®
监管等级:
别名:

Solute carrier family 30 member 8, ZnT-8, ZNT8

序列号:
Q8IWU4
来源:
E.coli
种属:
Human
标签:
His
序列:
1-70aa
预估分子量:
7.7 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Metabolism
Human SLC30A8 Protein
规格 & 价格: cart
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Human SLC30A8 Protein
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human SLC30A8 Protein
Recombinant human SLC30A8 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 8q24.11 by HGNC 8q24.11 by Entrez Gene 8q24.11 by Ensembl
SLC30A8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer.


功能:
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells.


亚细胞位置:
Cell membrane Multi-pass membrane protein Cytoplasmic vesicle Secretory vesicle membrane Multi-pass membrane protein Associated with insulin and glucagon secretory granules.


该产品尚未在任何出版物中被引用。

[1].
"Meta-analysis and functional effects of the SLC30A8 rs13266634 polymorphism on isolated human pancreatic islets."

[2].
"Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk."

[3].
"The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study."

[4].
"SLC30A8 (ZnT8) Polymorphism is Associated with Young Age at Type 1 Diabetes Onset."

[5].
"Association between anti-ZnT8 autoantibody specificities and SLC30A8 Arg325Trp variant in Japanese patients with type 1 diabetes."
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