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AKR1C1 (基因名), Aldo-keto reductase family 1 member C1 (蛋白名), ak1c1_human.
产品名称:

Human AKR1C1/ Aldo-keto reductase family 1 member C1 Recombinant Protein
醛酮还原酶家族成员C1

货号:

R14181h

商标:
EIAab®
监管等级:
别名:

20-alpha-hydroxysteroid dehydrogenase, Chlordecone reductase homolog HAKRC, Dihydrodiol dehydrogenase 1/2, High-affinity hepatic bile acid-binding protein, Indanol dehydrogenase, Trans-1, 2-dihydrobenzene-1, 2-diol dehydrogenase, 20-alpha-HSD, DD1/DD2, HBAB, DDH, DDH1

序列号:
Q04828
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human AKR1C1 Protein
规格 & 价格: cart
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Human AKR1C1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 10p15.1 by HGNC 10p15.1 by Entrez Gene 10p15.1 by Ensembl
AKR1C1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Monomer.


功能:
Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.


亚细胞位置:
Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk."

[2].
"Genetic polymorphisms in the oxidative stress pathway and susceptibility to non-Hodgkin lymphoma."

[3].
"Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids."

[4].
"Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes."

[5].
"Characterization of a human 20alpha-hydroxysteroid dehydrogenase."

[6].
"Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells."

[7].
"Regulation of human dihydrodiol dehydrogenase by Michael acceptor xenobiotics."

[8].
"Genomic organization and chromosomal localization of a novel human hepatic dihydrodiol dehydrogenase with high affinity bile acid binding."

[9].
"cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family."

[10].
"Human variation in alcohol response is influenced by variation in neuronal signaling genes."
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