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AKR1C2 (基因名), Aldo-keto reductase family 1 member C2 (蛋白名), ak1c2_human.
产品名称:

Human AKR1C2/ Aldo-keto reductase family 1 member C2 Recombinant Protein
类阿尔多酮还原酶家族1成员C2

货号:

R2111h

商标:
EIAab®
监管等级:
别名:

3-alpha-HSD3, Chlordecone reductase homolog HAKRD, Dihydrodiol dehydrogenase 2, Dihydrodiol dehydrogenase/bile acid-binding protein, Trans-1, 2-dihydrobenzene-1, 2-diol dehydrogenase, Type III 3-alpha-hydroxysteroid dehydrogenase, DD-2, DD/BABP, DDH2

序列号:
P52895
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human AKR1C2 Protein
规格 & 价格: cart
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Human AKR1C2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 10p15.1 by HGNC 10p15.1 by Entrez Gene 10p15.1 by Ensembl
AKR1C2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.


亚细胞位置:
Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"Sequence of the cDNA of a human dihydrodiol dehydrogenase isoform (AKR1C2) and tissue distribution of its mRNA."

[2].
"Why boys will be boys: two pathways of fetal testicular androgen biosynthesis are needed for male sexual differentiation."

[3].
"Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer."

[4].
"Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk."

[5].
"Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate."

[6].
"Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution."

[7].
"Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes."

[8].
"Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells."

[9].
"Structure of a gene coding for human dihydrodiol dehydrogenase/bile acid-binding protein."

[10].
"Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer."
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