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AKTIP (基因名), AKT-interacting protein (蛋白名), aktip_human.
产品名称:

Human AKTIP/ AKT-interacting protein Recombinant Protein
Akt相互作用蛋白

货号:

R14178h

商标:
EIAab®
监管等级:
别名:

Ft1, Fused toes protein homolog, FTS

序列号:
Q9H8T0
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human AKTIP Protein
规格 & 价格: cart
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Human AKTIP Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 16q12.2 by HGNC 16q12.2 by Entrez Gene 16q12.2 by Ensembl
AKTIP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Component of the FTS/Hook/FHIP complex (FHF complex), composed of AKTIP/FTS, FAM160A2, and one or more members of the Hook family of proteins HOOK1, HOOK2, and HOOK3. May interact directly with HOOK1, HOOK2 and HOOK3. The FHF complex associates with the homotypic vesicular sorting complex (the HOPS complex). Also interacts with AKT1.


功能:
Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.


亚细胞位置:
Cytoplasm Cell membrane Peripheral membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Association between AKT1 but not AKTIP genetic variants and increased risk for suicidal behavior in bipolar patients."

[2].
"Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival."

[3].
"An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex."

[4].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[5].
"Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt."

[6].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[7].
"Ft1, a novel gene related to ubiquitin-conjugating enzymes, is deleted in the Fused toes mouse mutation."

[8].
"A cDNA encoding the calcitonin gene-related peptide type 1 receptor."

[9].
"Architecture of the human interactome defines protein communities and disease networks."

[10].
"Lack of association between genetic polymorphism of FTO, AKT1 and AKTIP in childhood overweight and obesity."
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