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SLC31A1 (基因名), High affinity copper uptake protein 1 (蛋白名), copt1_human.
产品名称:

Human SLC31A1/ High affinity copper uptake protein 1 Recombinant Protein
高亲和力铜摄取蛋白质1

货号:

R1418h

商标:
EIAab®
监管等级:
别名:

Copper transporter 1, Solute carrier family 31 member 1, hCTR1, COPT1, CTR1

序列号:
O15431
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Signal Transduction
Human SLC31A1 Protein
规格 & 价格: cart
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Human SLC31A1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 9q32 by HGNC 9q32 by Entrez Gene 9q32 by Ensembl
SLC31A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homotrimer.


功能:
High-affinity, saturable copper transporter involved in dietary copper uptake.


亚细胞位置:
Cell membrane Multi-pass membrane protein Localizes to the apical membrane in intestinal epithelial cells.



[1].
"hCTR1: a human gene for copper uptake identified by complementation in yeast."

[2].
"Protein kinase inhibitors emodin and dichloro-ribofuranosylbenzimidazole modulate the cellular accumulation and cytotoxicity of cisplatin in a schedule-dependent manner."

[3].
"Enhanced delivery of cisplatin to intraperitoneal ovarian carcinomas mediated by the effects of bortezomib on the human copper transporter 1."

[4].
"Human copper transporter Ctr1 is functional in Drosophila, revealing a high degree of conservation between mammals and insects."

[5].
"Copper transporters and the cellular pharmacology of the platinum-containing cancer drugs."

[6].
"The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity."

[7].
"Reactivity of platinum-based antitumor drugs towards a Met- and His-rich 20mer peptide corresponding to the N-terminal domain of human copper transporter 1."

[8].
"Searching for genes for cleft lip and/or palate based on breakpoint analysis of a balanced translocation t(9;17)(q32;q12)."

[9].
"Role of copper transporters in resistance to platinating agents."

[10].
"Mechanistic comparison of human high-affinity copper transporter 1-mediated transport between copper ion and cisplatin."
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