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DCK (基因名), Deoxycytidine kinase (蛋白名), dck_human.
产品名称:

Human DCK/ Deoxycytidine kinase Recombinant Protein
脱氧胞嘧啶核苷激

货号:

R8892h

商标:
EIAab®
监管等级:
别名:

dCK

序列号:
P27707
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human DCK Protein
规格 & 价格: cart
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Human DCK Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 4q13.3 by HGNC 4q13.3 by Entrez Gene 4q13.3 by Ensembl
DCK Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer.


功能:
Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。

[1].
"[Correlation of deoxycytidine kinase gene expression with fludarabine resistance in patients with chronic lymphocytic leukemia]."

[2].
"Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase."

[3].
"Twenty novel genetic variations and haplotype structures of the DCK gene encoding human deoxycytidine kinase (dCK)."

[4].
"An association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients."

[5].
"Novel deoxycytidine kinase gene polymorphisms: a population screening study in Caucasian healthy volunteers."

[6].
"The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation."

[7].
"Association between single nucleotide polymorphisms in deoxycytidine kinase and treatment response among acute myeloid leukaemia patients."

[8].
"Structure of human dCK suggests strategies to improve anticancer and antiviral therapy."

[9].
"Human deoxycytidine kinase is located in the cell nucleus."

[10].
"Characterization of human deoxycytidine kinase. Correlation with cDNA sequences."
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