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DDAH1 (基因名), N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (蛋白名), ddah1_human.
产品名称:

Human DDAH1/ N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 Recombinant Protein
DDAH-1

货号:

R0300h

商标:
EIAab®
监管等级:
别名:

DDAHI, Dimethylargininase-1, DDAH-1, DDAH

序列号:
O94760
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
Human DDAH1 Protein
规格 & 价格: cart
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Human DDAH1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1p22.3 by HGNC 1p22.3 by Entrez Gene 1p22.3 by Ensembl
DDAH1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Monomer.


功能:
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。

[1].
"Circulating methylarginine levels and the decline in renal function in patients with chronic kidney disease are modulated by DDAH1 polymorphisms."

[2].
"A novel loss-of-function DDAH1 promoter polymorphism is associated with increased susceptibility to thrombosis stroke and coronary heart disease."

[3].
"Sequence variation in DDAH1 and DDAH2 genes is strongly and additively associated with serum ADMA concentrations in individuals with type 2 diabetes."

[4].
"Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide."

[5].
"Disruption of methylarginine metabolism impairs vascular homeostasis."
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