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首页  >  重组蛋白  >  Human ICOSLG Recombinant Protein
ICOSLG (基因名), ICOS ligand (蛋白名), icosl_human.
产品名称:

Human ICOSLG/ ICOS ligand Recombinant Protein
ICOS配体

货号:

R15092h

商标:
EIAab®
监管等级:
别名:

B7 homolog 2, B7-like protein Gl50, B7-related protein 1, B7-H2, B7RP-1, CD275, B7H2, B7RP1, ICOSL, KIAA0653

序列号:
O75144
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ICOSLG Protein
规格 & 价格: cart
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Human ICOSLG Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 21q22.3 by HGNC 21q22.3 by Entrez Gene 21q22.3 by Ensembl
ICOSLG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.


亚细胞位置:
Membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS."

[2].
"Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."

[3].
"Multiple common variants for celiac disease influencing immune gene expression."

[4].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[5].
"An approach based on a genome-wide association study reveals candidate loci for narcolepsy."

[6].
"Impact of female cigarette smoking on circulating B cells in vivo: the suppressed ICOSLG, TCF3, and VCAM1 gene functional network may inhibit normal cell function."

[7].
"Analysis of 39 Crohn's disease risk loci in Swedish inflammatory bowel disease patients."

[8].
"Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects."

[9].
"[Expression of B7-related protein-1 on human coronary artery endothelial cells and its clinical significance]."

[10].
"[Expression of ICOSL on human coronary artery endothelial cells and its being interferentialed by ox-LDL]."
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