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IL6R (基因名), Interleukin-6 receptor subunit alpha (蛋白名), il6ra_human.
产品名称:

Human IL6R/ Interleukin-6 receptor subunit alpha Recombinant Protein
白介素6受体α亚基

货号:

R1815h

商标:
EIAab®
监管等级:
别名:

IL-6R 1, Membrane glycoprotein 80, gp80, CD126, IL-6 receptor subunit alpha

序列号:
P08887
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Human IL6R Protein
规格 & 价格: cart
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Human IL6R Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1q21.3 by HGNC 1q21.3 by Entrez Gene 1q21.3 by Ensembl
IL6R Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Hexamer of two molecules each of IL6, IL6R and IL6ST.


功能:
Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity.


亚细胞位置:
Isoform 2 Secreted


该产品尚未在任何出版物中被引用。

[1].
"Interleukin-6 receptor gene, plasma C-reactive protein, and diabetes risk in women."

[2].
"Interleukin-6 (IL-6) and receptor (IL6-R) gene haplotypes associate with amniotic fluid protein concentrations in preterm birth."

[3].
"IL-6 receptor, IL-8 receptor and TNF-alpha238 (G/A) polymorphisms are not associated with Beh?et's disease in patients of German or Turkish origin."

[4].
"Molecular screening and association analyses of the interleukin 6 receptor gene variants with type 2 diabetes, diabetic nephropathy, and insulin sensitivity."

[5].
"Polymorphisms in the IL-6 receptor (IL-6R) gene: strong evidence that serum levels of soluble IL-6R are genetically influenced."

[6].
"Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites."

[7].
"Structure of the extracellular domains of the human interleukin-6 receptor alpha -chain."

[8].
"The cytoplasmic domain of the interleukin-6 receptor gp80 mediates its basolateral sorting in polarized madin-darby canine kidney cells."

[9].
"Structure-function analysis of human IL-6 receptor: dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130."

[10].
"A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex."
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