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ITGB3 (基因名), Integrin beta-3 (蛋白名), itb3_human.
产品名称:

Human ITGB3/ Integrin beta-3 Recombinant Protein
整合素β3

货号:

R15079h

商标:
EIAab®
监管等级:
别名:

Platelet membrane glycoprotein IIIa, GPIIIa, CD61, GP3A

序列号:
P05106
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human ITGB3 Protein
规格 & 价格: cart
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Human ITGB3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 17q21.32 by HGNC 17q21.32 by Entrez Gene 17q21.32 by Ensembl
ITGB3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
(Microbial infection) Interacts with HIV-1 Tat (PubMed:10397733). ITGAV:ITGB3 interacts with AGRA2 (PubMed:16982628).


功能:
(Microbial infection) Integrin ITGAV:ITGB3 acts as a receptor for herpes virus 8/HHV-8 (PubMed:18045938). Integrin ITGAV:ITGB3 acts as a receptor for coxsackievirus A9 (PubMed:7519807). Acts as a receptor for Hantaan virus (PubMed:9618541). Integrin ITGAV:ITGB3 acts as a receptor for cytomegalovirus/HHV-5 (PubMed:15834425). Integrin ITGA5:ITGB3 acts as a receptor for human metapneumovirus (PubMed:24478423). Integrin ITGAV:ITGB3 acts aP05556s a receptor for human parechovirus 1 (PubMed:11160695). Integrin ITGAV:ITGB3 acts as a receptor for west nile virus (PubMed:23658209). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions (PubMed:10397733).


亚细胞位置:
Cell membrane Single-pass type I membrane protein Cell projection Lamellipodium membrane Cell junction Focal adhesion


该产品尚未在任何出版物中被引用。

[1].
"AlphaIIbbeta3 integrin: new allelic variants in Glanzmann thrombasthenia, effects on ITGA2B and ITGB3 mRNA splicing, expression, and structure-function."

[2].
"The Leu33Pro polymorphism in the ITGB3 gene does not modify BRCA1/2-associated breast or ovarian cancer risks: results from a multicenter study among 15,542 BRCA1 and BRCA2 mutation carriers."

[3].
"Association and gene-gene interaction of SLC6A4 and ITGB3 in autism."

[4].
"[Association of the integrin gene polymorphisms with ischemic stroke and plasma lipid levels]."

[5].
"[Distributions of polymorphisms of genes of some components of hemostasis in patients with ischemic heart disease]."

[6].
"Evidence for epistasis between SLC6A4 and ITGB3 in autism etiology and in the determination of platelet serotonin levels."

[7].
"Frequency of genetic polymorphisms of COX1, GPIIIa and P2Y1 in a Chinese population and association with attenuated response to aspirin."

[8].
"Integrin beta 3 genotype influences asthma and allergy phenotypes in the first 6 years of life."

[9].
"The association between type 2 diabetes mellitus and A1/A2 polymorphism of glycoprotein IIIa gene."

[10].
"ITGB3 shows genetic and expression interaction with SLC6A4."
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