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MAGEA1 (基因名), Melanoma-associated antigen 1 (蛋白名), maga1_human.
产品名称:

Human MAGEA1/ Melanoma-associated antigen 1 Recombinant Protein
与黑素瘤相关抗原1

货号:

R1330h

商标:
EIAab®
监管等级:
别名:

Antigen MZ2-E, Cancer/testis antigen 1.1, MAGE-1 antigen, CT1.1, MAGE1, MAGE1A

序列号:
P43355
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human MAGEA1 Protein
规格 & 价格: cart
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: Xq28 by HGNC Xq28 by Entrez Gene Xq28 by Ensembl
MAGEA1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with SNW1 and HDCA1.


功能:
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.


亚细胞位置:
Cytoplasm Nucleus


该产品尚未在任何出版物中被引用。

[1].
"[The genetic polymorphism of melanoma-associated antigen 1 in Chinese normal donors and hepatoma patients]."

[2].
"MAGE-1 gene product is a cytoplasmic protein."

[3].
"Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes."

[4].
"A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma."

[5].
"The melanoma-associated antigen 1 (MAGEA1) protein stimulates the E3 ubiquitin-ligase activity of TRIM31 within a TRIM31-MAGEA1-NSE4 complex."

[6].
"Frequent MAGE mutations in human melanoma."

[7].
"Expression of tumor-specific antigen MAGE, GAGE and BAGE in ovarian cancer tissues and cell lines."

[8].
"MAGE-A1 expression is associated with good prognosis in neuroblastoma tumors."

[9].
"[Expression of melanoma antigen-1, 3 genes in human intrahepatic cholangiocarcinoma and its clinical significance]."

[10].
"MAGE-A1, GAGE and NY-ESO-1 cancer/testis antigen expression during human gonadal development."
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