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NENF (基因名), Neudesin (蛋白名), nenf_human.
产品名称:

Human NENF/ Neudesin Recombinant Protein
Neudesin

货号:

R13396h

商标:
EIAab®
监管等级:
别名:

Cell immortalization-related protein 2, Neuron-derived neurotrophic factor, Protein GIG47, Secreted protein of unknown function, SPUF protein, CIR2, SPUF

序列号:
Q9UMX5
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human NENF Protein
规格 & 价格: cart
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Human NENF Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1q32.3 by HGNC 1q32.3 by Entrez Gene 1q32.3 by Ensembl
NENF Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity). Plays a role in the human tumorigenesis (PubMed:22748190).


亚细胞位置:
Secreted Extracellular space


该产品尚未在任何出版物中被引用。

[1].
"Neudesin, a novel secreted protein with a unique primary structure and neurotrophic activity."

[2].
"Up-regulation of CIR1/CROC1 expression upon cell immortalization and in tumor-derived human cell lines."

[3].
"Neurotrophic activity of neudesin, a novel extracellular heme-binding protein, is dependent on the binding of heme to its cytochrome b5-like heme/steroid-binding domain."

[4].
"Breast cancer proteomics by laser capture microdissection, sample pooling, 54-cm IPG IEF, and differential iodine radioisotope detection."

[5].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[6].
"Architecture of the human interactome defines protein communities and disease networks."

[7].
"Membrane Associated Progesterone Receptors: Promiscuous Proteins with Pleiotropic Functions - Focus on Interactions with Cytochromes P450."

[8].
"The BioPlex Network: A Systematic Exploration of the Human Interactome."

[9].
"Panorama of ancient metazoan macromolecular complexes."

[10].
"A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface."
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