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P2RY12 (基因名), P2Y purinoceptor 12 (蛋白名), p2y12_human.
产品名称:

Human P2RY12/ P2Y purinoceptor 12 Recombinant Protein
P2Y嘌呤受体12

货号:

R12345h

商标:
EIAab®
监管等级:
别名:

ADP-glucose receptor, P2T(AC), P2Y(AC), P2Y(cyc), P2Y12 platelet ADP receptor, SP1999, ADPG-R, P2Y(ADP), P2Y12, HORK3

序列号:
Q9H244
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human P2RY12 Protein
规格 & 价格: cart
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Human P2RY12 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 3q25.1 by HGNC 3q25.1 by Entrez Gene 3q25.1 by Ensembl
P2RY12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation.


亚细胞位置:
Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Molecular cloning of the platelet P2T(AC) ADP receptor: pharmacological comparison with another ADP receptor, the P2Y(1) receptor."

[2].
"[Genetic variants of platelet ADP receptor P2Y12 associated with changed platelet functional activity and development of cardiovascular diseases]."

[3].
"Common variation in the platelet receptor P2RY12 gene is associated with residual on-clopidogrel platelet reactivity in patients undergoing elective percutaneous coronary interventions."

[4].
"Coexisting polymorphisms of P2Y12 and CYP2C19 genes as a risk factor for persistent platelet activation with clopidogrel."

[5].
"Purinergic receptor P2Y, G-protein coupled, 12 gene variants and risk of incident ischemic stroke, myocardial infarction, and venous thromboembolism."

[6].
"P2Y12 polymorphisms and antiplatelet effects of aspirin in patients with coronary artery disease."

[7].
"Platelet receptor P2RY12 haplotypes predict restenosis after percutaneous coronary interventions."

[8].
"Genetic polymorphisms of the platelet receptors P2Y(12), P2Y(1) and GP IIIa and response to aspirin and clopidogrel."

[9].
"Role of the T744C polymorphism of the P2Y12 gene on platelet response to a 600-mg loading dose of clopidogrel in 597 patients with non-ST-segment elevation acute coronary syndrome."

[10].
"Gene sequence variations of the platelet P2Y12 receptor are associated with coronary artery disease."
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