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PAEP (基因名), Glycodelin (蛋白名), paep_human.
产品名称:

Human PAEP/ Glycodelin Recombinant Protein
胎盘蛋白

货号:

R10200h

商标:
EIAab®
监管等级:
别名:

Placental protein 14, Pregnancy-associated endometrial alpha-2 globulin, Progestagen-associated endometrial protein, Progesterone-associated endometrial protein, Zona-binding inhibitory factor-1, PP14, PAEG, ZIF-1, GD

序列号:
P09466
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human PAEP Protein
规格 & 价格: cart
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Human PAEP Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 9q34.3 by HGNC 9q34.3 by Entrez Gene 9q34.3 by Ensembl
PAEP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer (PubMed:25422905, PubMed:9239694).


功能:
Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities (PubMed:9918684, PubMed:7531163). Glycodelin-C stimulates binding of spermatozoa to the zona pellucida (PubMed:17192260). Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa (PubMed:12672671). Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa (PubMed:15883155).


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"Cumulus oophorus-associated glycodelin-C displaces sperm-bound glycodelin-A and -F and stimulates spermatozoa-zona pellucida binding."

[2].
"Purification and characterization of an immunomodulatory endometrial protein, glycodelin."

[3].
"Gender-specific glycosylation of human glycodelin affects its contraceptive activity."

[4].
"Glycodelin from seminal plasma is a differentially glycosylated form of contraceptive glycodelin-A."

[5].
"Structural analysis of the oligosaccharides derived from glycodelin, a human glycoprotein with potent immunosuppressive and contraceptive activities."

[6].
"The human placental protein 14 (PP14) gene is localized on chromosome 9q34."

[7].
"The dimeric crystal structure of the human fertility lipocalin glycodelin reveals a protein scaffold for the presentation of complex glycans."

[8].
"Glycodelin A triggers T cell apoptosis through a novel calcium-independent galactose-binding lectin activity."

[9].
"Plexin-B1, glycodelin and MMP7 expression in the human fallopian tube and in the endometrium."

[10].
"Correlation between symptoms of pain and peritoneal fluid inflammatory cytokine concentrations in endometriosis."
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