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PENK (基因名), Proenkephalin-A (蛋白名), penk_human.
产品名称:

Human PENK/ Proenkephalin-A Recombinant Protein
脑啡肽原A

货号:

R0279h

商标:
EIAab®
监管等级:
序列号:
P01210
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Human PENK Protein
规格 & 价格: cart
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Human PENK Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 8q12.1 by HGNC 8q12.1 by Entrez Gene 8q12.1 by Ensembl
PENK Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum.


亚细胞位置:
Secreted



[1].
"Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expression."

[2].
"The opioid system in alcohol and drug dependence: family-based association study."

[3].
"Isolation and structural organization of the human preproenkephalin gene."

[4].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[5].
"The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature."

[6].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."

[7].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[8].
"Genetical genomic determinants of alcohol consumption in rats and humans."

[9].
"Many sequence variants affecting diversity of adult human height."

[10].
"Proenkephalin assists stress-activated apoptosis through transcriptional repression of NF-kappaB- and p53-regulated gene targets."
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