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ACPP (基因名), Prostatic acid phosphatase (蛋白名), ppap_human.
产品名称:

Human ACPP/ Prostatic acid phosphatase Recombinant Protein
前列腺酸性磷酸

货号:

R0168h

商标:
EIAab®
监管等级:
别名:

5'-nucleotidase, Ecto-5'-nucleotidase, Thiamine monophosphatase, 5'-NT, TMPase, PAP

序列号:
P15309
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human ACPP Protein
规格 & 价格: cart
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Human ACPP Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 3q22.1 by HGNC 3q22.1 by Entrez Gene 3q22.1 by Ensembl
ACPP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer; dimer formation is required for phosphatase activity.


功能:
Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.


亚细胞位置:
Isoform 2 Cell membrane Single-pass type I membrane protein Lysosome membrane Single-pass type I membrane protein Appears to shuttle between the cell membrane and intracellular vesicles. Colocalizes with FLOT1 at cell membrane and in intracellular vesicles (PubMed:17638863). Colocalizes with LAMP2 on the lysosome membrane (PubMed:17897319).


该产品尚未在任何出版物中被引用。

[1].
"Structural origins of L(+)-tartrate inhibition of human prostatic acid phosphatase."

[2].
"Structure of human prostatic acid phosphatase gene."

[3].
"Molecular cloning and sequence analysis of cDNA encoding human prostatic acid phosphatase."

[4].
"Prostatic acid phosphatase expression in human tissues."

[5].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
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