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SLC5A2 (基因名), Sodium/glucose cotransporter 2 (蛋白名), sc5a2_human.
产品名称:

Human SLC5A2/ Sodium/glucose cotransporter 2 Recombinant Protein
钠/葡萄糖转运蛋白2

货号:

R0659h

商标:
EIAab®
监管等级:
别名:

Low affinity sodium-glucose cotransporter, Solute carrier family 5 member 2, Na(+)/glucose cotransporter 2, SGLT2

序列号:
P31639
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human SLC5A2 Protein
规格 & 价格: cart
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Human SLC5A2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 16p11.2 by HGNC 16p11.2 by Entrez Gene 16p11.2 by Ensembl
SLC5A2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.


亚细胞位置:
Membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Novel compound heterozygous mutations in SLC5A2 are responsible for autosomal recessive renal glucosuria."

[2].
"Localization of the Na+/glucose cotransporter gene SGLT2 to human chromosome 16 close to the centromere."

[3].
"Cloning of a human kidney cDNA with similarity to the sodium-glucose cotransporter."

[4].
"Twenty-one additional cases of familial renal glucosuria: absence of genetic heterogeneity, high prevalence of private mutations and further evidence of volume depletion."

[5].
"Thioglycosides as inhibitors of hSGLT1 and hSGLT2: potential therapeutic agents for the control of hyperglycemia in diabetes."

[6].
"A novel missense mutation in SLC5A2 encoding SGLT2 underlies autosomal-recessive renal glucosuria and aminoaciduria."

[7].
"Molecular analysis of the SGLT2 gene in patients with renal glucosuria."

[8].
"Autosomal recessive renal glucosuria attributable to a mutation in the sodium glucose cotransporter (SGLT2)."

[9].
"Identification of ten novel SLC5A2 mutations and determination of the renal threshold for glucose excretion in Chinese patients with familial renal glucosuria."

[10].
"MicroRNA-296, a suppressor non-coding RNA, downregulates SGLT2 expression in lung cancer."
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