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SIPA1L1 (基因名), Signal-induced proliferation-associated 1-like protein 1 (蛋白名), si1l1_human.
产品名称:

Human SIPA1L1/ Signal-induced proliferation-associated 1-like protein 1 Recombinant Protein
信号诱导增殖相关蛋白1样蛋白1

货号:

R6550h

商标:
EIAab®
监管等级:
别名:

High-risk human papilloma viruses E6 oncoproteins targeted protein 1, E6-targeted protein 1, SIPA1-like protein 1, E6TP1, KIAA0440

序列号:
O43166
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human SIPA1L1 Protein
规格 & 价格: cart
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Human SIPA1L1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 14q24.1 by HGNC 14q24.1 by Entrez Gene 14q24.1 by Ensembl
SIPA1L1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with DLG4, PDLIM5, PDLIM7 and LZTS3. Interacts with the actin cytoskeleton (By similarity). Interacts (via PDZ domain) with EPHA4 (via PDZ motif); controls neuronal morphology through regulation of the RAP1 (RAP1A or RAP1B) and RAP2 (RAP2A, RAP2B or RAP2C) GTPases. Interacts with HPV E6.


功能:
Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F-actin. Contributes to the regulation of dendritic spine morphogenesis.


亚细胞位置:
Cytoplasm Cytoskeleton Cell junction Synapse Postsynaptic cell membrane Postsynaptic density Cell junction Synapse Synaptosome Associated with the actin cytoskeleton. Detected at synapses and dendritic spines of cultured hippocampal neurons (By similarity).


该产品尚未在任何出版物中被引用。

[1].
"The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation."

[2].
"Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction."

[3].
"Analysis of the roles of E6 binding to E6TP1 and nuclear localization in the human papillomavirus type 31 life cycle."

[4].
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."

[5].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
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