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SIRT3 (基因名), NAD-dependent deacetylase sirtuin-3, mitochondrial (蛋白名), sirt3_human.
产品名称:

Human SIRT3/ NAD-dependent deacetylase sirtuin-3, mitochondrial Recombinant Protein
hSIRT3

货号:

R2135h

商标:
EIAab®
监管等级:
别名:

SIR2-like protein 3, hSIRT3, SIR2L3

序列号:
Q9NTG7
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Epigenetics
Human SIRT3 Protein
规格 & 价格: cart
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Human SIRT3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 11p15.5 by HGNC 11p15.5 by Entrez Gene 11p15.5 by Ensembl
SIRT3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with NDUFA9, ACSS1, IDH2 and GDH.


功能:
NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.


亚细胞位置:
Mitochondrion matrix


该产品尚未在任何出版物中被引用。

[1].
"The human SIRT3 protein deacetylase is exclusively mitochondrial."

[2].
"Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5."

[3].
"Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2."

[4].
"A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages."

[5].
"The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase."
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