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SMTNL1 (基因名), Smoothelin-like protein 1 (蛋白名), smtl1_human.
产品名称:

Human SMTNL1/ Smoothelin-like protein 1 Recombinant Protein
Smoothelin-like蛋白1

货号:

R2278h

商标:
EIAab®
监管等级:
序列号:
A8MU46
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human SMTNL1 Protein
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Human SMTNL1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 11q12.1 by HGNC 11q12.1 by Entrez Gene 11q12.1 by Ensembl
SMTNL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with PPP1R12A.


功能:
Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity.


亚细胞位置:
Cytoplasm Myofibril Cytoplasm Myofibril Sarcomere I band Cytoplasm Myofibril Sarcomere M line Nucleus Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm (By similarity). Phosphorylation at Ser-301 promotes translocation to the nucleus (By similarity).


该产品尚未在任何出版物中被引用。

[1].
"Smoothelin-like 1 protein regulates myosin phosphatase-targeting subunit 1 expression during sexual development and pregnancy."

[2].
"Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle."

[3].
"Modulation of smooth muscle contractility by CHASM, a novel member of the smoothelin family of proteins."

[4].
"A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome."

[5].
"Pregnancy and Smoothelin-like Protein 1 (SMTNL1) Deletion Promote the Switching of Skeletal Muscle to a Glycolytic Phenotype in Human and Mice."

[6].
"Mapping and functional characterization of the murine smoothelin-like 1 promoter."

[7].
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."

[8].
"Tropomyosin-binding properties of the CHASM protein are dependent upon its calponin homology domain."

[9].
"The role of the calponin homology domain of smoothelin-like 1 (SMTNL1) in myosin phosphatase inhibition and smooth muscle contraction."

[10].
"Human chromosome 11 DNA sequence and analysis including novel gene identification."
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