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STAT6 (基因名), Signal transducer and activator of transcription 6 (蛋白名), stat6_human.
产品名称:

Human STAT6/ Signal transducer and activator of transcription 6 Recombinant Protein
信号转换器和转录激活因子

货号:

R1737h

商标:
EIAab®
监管等级:
别名:

IL-4 Stat

序列号:
P42226
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human STAT6 Protein
规格 & 价格: cart
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Human STAT6 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 12q13 by HGNC 12q13 by Entrez Gene 12q13 by Ensembl
STAT6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Forms a homodimer or a heterodimer with a related family member (By similarity). Interacts with NCOA1 via its C-terminal LXXLL motif.


功能:
Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling.


亚细胞位置:
Cytoplasm Nucleus Translocated into the nucleus in response to phosphorylation.


该产品尚未在任何出版物中被引用。

[1].
"T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6."

[2].
"Polymorphisms of interleukin (IL)-4 receptor alpha and signal transducer and activator of transcription-6 (Stat6) are associated with increased IL-4Ralpha-Stat6 signalling in lymphocytes and elevated serum IgE in patients with Graves' disease."

[3].
"The G2964A polymorphism of the STAT6 gene in inflammatory bowel disease."

[4].
"Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain."

[5].
"Linkage and association studies of STAT6 gene polymorphisms and allergic diseases."

[6].
"An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1."

[7].
"An interleukin-4-induced transcription factor: IL-4 Stat."

[8].
"A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study."

[9].
"Replication of genetic association studies in asthma and related phenotypes."

[10].
"Risk of meningioma and common variation in genes related to innate immunity."
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