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ZFP36 (基因名), mRNA decay activator protein ZFP36 (蛋白名), ttp_human.
产品名称:

Human ZFP36/ mRNA decay activator protein ZFP36 Recombinant Protein
Tristetraprolin蛋白

货号:

R5400h

商标:
EIAab®
监管等级:
别名:

G0/G1 switch regulatory protein 24, Growth factor-inducible nuclear protein NUP475, Tristetraprolin, Zinc finger protein 36, Zfp-36, G0S24, NUP475, RNF162A, TIS11A, TTP

序列号:
P26651
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Human ZFP36 Protein
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Human ZFP36 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 19q13.1 by HGNC 19q13.1 by Entrez Gene 19q13.1 by Ensembl
ZFP36 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
(Microbial infection) Interacts (via C-terminus) with HTLV-1 TAX (via C-terminus); this interaction inhibits HTLV-1 TAX to transactivate viral long terminal repeat (LTR) promoter (PubMed:14679154).


功能:
(Microbial infection) Negatively regulates HTLV-1 TAX-dependent transactivation of viral long terminal repeat (LTR) promoter.


亚细胞位置:
Nucleus Cytoplasm (Microbial infection) Colocalizes with HTLV-1 TAX in the nucleus and the cytoplasm in a region surrounding the nucleus.


该产品尚未在任何出版物中被引用。

[1].
"ZFP36L1 is regulated by growth factors and cytokines in keratinocytes and influences their VEGF production."

[2].
"Phosphorylation of human tristetraprolin in response to its interaction with the Cbl interacting protein CIN85."

[3].
"Identification of TTP mRNA targets in human dendritic cells reveals TTP as a critical regulator of dendritic cell maturation."

[4].
"TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements."

[5].
"Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesis."

[6].
"Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay."

[7].
"Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1."

[8].
"Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR."

[9].
"The role of mRNA turnover in the regulation of tristetraprolin expression: evidence for an extracellular signal-regulated kinase-specific, AU-rich element-dependent, autoregulatory pathway."

[10].
"Direct association of tristetraprolin with the nucleoporin CAN/Nup214."
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