Rat Creb1/ Cyclic AMP-responsive element-binding protein 1 CLIA Kit
cAMP反应元件结合蛋白1

货号:

U1318r

商标:

EIAab^®

监管等级:

RUO

别名:

CREB-1, Creb-1

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

39-2500pg/mL

特异性:

Natural and recombinant rat Cyclic AMP-responsive element-binding protein 1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Neurosciences

规格 & 价格:

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Rat Creb1 CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

数据
文献 ( 3 )
序列 / 3D
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通用注释

亚单元:

Interacts with PPRC1. Binds DNA as a dimer. Interacts, through the bZIP domain, with the coactivators TORC1/CRTC1, TORC2/CRTC2 and TORC3/CRTC3 (By similarity). When phosphorylated on Ser-133, binds CREBBP. Interacts with ARRB1. Interacts (phosphorylated form) with TOX3. Binds to HIPK2 (By similarity). Interacts with SGK1 (By similarity). Interacts with CREBL2; regulates CREB1 phosphorylation, stability and transcriptional activity.

功能:

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

亚细胞位置:

Nucleus

数据库链接

UniGene:

Rn.90061

SMR:

P15337

STRING:

10116.ENSRNOP00000018326

KEGG:

rno:81646

Pfam: