Human C8A/ Complement component C8 alpha chain CLIA Kit
补体成分C8α

货号:

U1970h

商标:

EIAab^®

监管等级:

RUO

别名:

Complement component 8 subunit alpha

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

1.56-100ng/mL

特异性:

Natural and recombinant human Complement component C8 alpha chain

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Human C8A CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

数据
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通用注释

亚单元:

Heterotrimer of 3 chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded. Component of the membrane attack complex (MAC). MAC assembly is initiated by proteolytic cleavage of C5 into C5a and C5b. C5b sequentially binds C6, C7, C8 and multiple copies of the pore-forming subunit C9.

功能:

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself.

亚细胞位置:

Secreted Cell membrane Multi-pass membrane protein Secreted as soluble protein. Inserts into the cell membrane of target cells.

数据库链接

UniGene:

Hs.93210

SMR:

P07357

STRING:

9606.ENSP00000354458

KEGG:

hsa:731

MIM: