C8a (基因名), Complement component C8 alpha chain (蛋白名), co8a_mouse.
产品名称:
Mouse C8a/ Complement component C8 alpha chain CLIA Kit
补体成分C8α
货号:
U1970m
商标:
EIAab®
监管等级:
别名:
Complement component 8 subunit alpha
检测方法:
CLIA
特异性:
Natural and recombinant mouse Complement component C8 alpha chain
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Heterotrimer of 3 chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded. Component of the membrane attack complex (MAC). MAC assembly is initiated by proteolytic cleavage of C5 into C5a and C5b. C5b sequentially binds C6, C7, C8 and multiple copies of the pore-forming subunit C9.
功能:
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself.
亚细胞位置:
Secreted
Cell membrane
Multi-pass membrane protein
Secreted as soluble protein. Inserts into the cell membrane of target cells (By similarity).
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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