Hdac10 (基因名), Polyamine deacetylase HDAC10 (蛋白名), hda10_rat.
产品名称:
Rat Hdac10/ Polyamine deacetylase HDAC10 CLIA Kit
货号:
U11381r
商标:
EIAab®
监管等级:
别名:
Histone deacetylase 10, HD10
检测方法:
CLIA
特异性:
Natural and recombinant rat Polyamine deacetylase HDAC10
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
Interacts with HDAC3. Interacts with HDAC2 and NCOR2/SMRT. Interacts with HSPA8/HSC70. Interacts with MSH2.
功能:
Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine. Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine. Histone deacetylase activity has been observed in vitro. Has also been shown to be involved in MSH2 deacetylation. The physiological relevance of protein/histone deacetylase activity is unclear and could be very weak. May play a role in the promotion of late stages of autophagy, possibly autophagosome-lysosome fusion and/or lysosomal exocytosis in neuroblastoma cells. May play a role in homologous recombination. May promote DNA mismatch repair.
亚细胞位置:
Cytoplasm
Nucleus
Excluded from nucleoli.
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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