Human JAM3/ Junctional adhesion molecule C CLIA Kit

货号:

U2825h

商标:

EIAab^®

监管等级:

RUO

别名:

JAM-2, Junctional adhesion molecule 3, JAM-3, UNQ859/PRO1868, JAM-C

检测方法:

CLIA

特异性:

Natural and recombinant human Junctional adhesion molecule C

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

关注

Human JAM3 CLIA Kit

邮箱 *

消息 *

Please 登录.

产品说明书

在线询价

数据
文献
序列 / 3D
反馈墙 (0)

通用注释

亚单元:

Interacts with JAM2. Interacts with ITGAM.

功能:

Participates in cell-cell adhesion. It is a counter-receptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN). The soluble form is a mediator of angiogenesis.

亚细胞位置:

Cell membrane Single-pass type I membrane protein Cell junction Desmosome Secreted Extracellular space In epithelial cells, it is expressed at desmosomes but not at tight junctions (PubMed:15194813). Localizes at the cell surface of endothelial cells; treatment of endothelial cells with vascular endothelial growth factor stimulates recruitment of JAM3 to cell-cell contacts (PubMed:15994945).

数据库链接

UniGene:

Hs.150718

SMR:

Q9BX67

KEGG:

hsa:83700

MIM:

606871

Pfam:

PF07686

Uniprot: