Jam3 (基因名), Junctional adhesion molecule C (蛋白名), jam3_mouse.
产品名称:
Mouse Jam3/ Junctional adhesion molecule C CLIA Kit
货号:
U2825m
商标:
EIAab®
监管等级:
别名:
JAM-2, Junctional adhesion molecule 3, JAM-3, JAM-C
检测方法:
CLIA
特异性:
Natural and recombinant mouse Junctional adhesion molecule C
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with JAM2. Interacts with ITGAM.
功能:
Participates in cell-cell adhesion. It is a counter-receptor for ITGAM mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN) (By similarity). The soluble form is a mediator of angiogenesis.
亚细胞位置:
Cell membrane
Single-pass type I membrane protein
Cell junction
Desmosome
Secreted
Extracellular space
In epithelial cells, it is expressed at desmosomes but not at tight junctions. Localizes at the cell surface of endothelial cells. Treatment of endothelial cells with vascular endothelial growth factor stimulates recruitment of JAM3 to cell-cell contacts.
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