Pig MAGED1/ Melanoma-associated antigen D1 CLIA Kit
与黑素瘤相关抗原D1

货号:

U6073p

商标:

EIAab^®

监管等级:

RUO

别名:

MAGE-D1 antigen

检测方法:

CLIA

特异性:

Natural and recombinant pig Melanoma-associated antigen D1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

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Pig MAGED1 CLIA Kit

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产品说明书

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数据
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序列 / 3D
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通用注释

亚单元:

Interacts with DLX5, DLX7 and MSX2 and forms homomultimers. Interacts with UNC5A. Interacts with TRIM28 and PJA1. Interacts with NGFR/p75NTR and RORA.

功能:

Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rhythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.

亚细胞位置:

Cytoplasm Cell membrane Peripheral membrane protein Nucleus Expression shifts from the cytoplasm to the plasma membrane upon stimulation with NGF.

数据库链接

UniGene:

Ssc.22086

SMR:

Q6ITT4

STRING:

9823.ENSSSCP00000013109

KEGG:

ssc:414852

Pfam: