O3FAR1 (基因名), Omega-3 fatty acid receptor 1 (蛋白名), o3fa1_human.
产品名称:
Human O3FAR1/ Omega-3 fatty acid receptor 1 CLIA Kit
ω-3脂肪酸受体1
货号:
U12801h
商标:
EIAab®
监管等级:
别名:
G-protein coupled receptor 120, G-protein coupled receptor 129, G-protein coupled receptor GT01, G-protein coupled receptor PGR4, GPR120, GPR129, PGR4
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
39-2500pg/mL
特异性:
Natural and recombinant human Omega-3 fatty acid receptor 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Signal Transduction
通用注释
亚单元:
Interacts with ARRB2 following docosahexaenoic acid (DHA) stimulation.
功能:
Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particulary in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediates the taste of fatty acids.
亚细胞位置:
Cell membrane
Multi-pass membrane protein
Colocalized with ARRB2 following DHA treatment.
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