Rat O3far1/ Omega-3 fatty acid receptor 1 CLIA Kit
ω-3脂肪酸受体1

货号:

U12801r

商标:

EIAab^®

监管等级:

RUO

别名:

G-protein coupled receptor 120, Gpr120

检测方法:

CLIA

特异性:

Natural and recombinant rat Omega-3 fatty acid receptor 1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Signal Transduction

规格 & 价格:

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Rat O3far1 CLIA Kit

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通用注释

亚单元:

Interacts with ARRB2 following docosahexaenoic acid (DHA) stimulation.

功能:

Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particulary in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect, but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation (By similarity). May mediates the taste of fatty acids.

亚细胞位置:

Cell membrane Multi-pass membrane protein Colocalized with ARRB2 following DHA treatment.

数据库链接

Uniprot:

Q2AC31

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