Chicken SBDS/ Ribosome maturation protein SBDS CLIA Kit

货号:

U14247c

商标:

EIAab^®

监管等级:

RUO

别名:

Shwachman-Bodian-Diamond syndrome protein homolog, RCJMB04_22m12

检测方法:

CLIA

特异性:

Natural and recombinant chicken Ribosome maturation protein SBDS

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Epigenetics

规格 & 价格:

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Chicken SBDS CLIA Kit

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通用注释

亚单元:

Associates with the 60S ribosomal subunit.

功能:

Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

亚细胞位置:

Cytoplasm Nucleus Nucleolus Nucleus Nucleoplasm Cytoplasm Cytoskeleton Spindle Primarily detected in the cytoplasm, and at low levels in nucleus and nucleolus. Detected at the mitotic spindle. Colocalizes with the microtubule organizing center during interphase (By similarity).

数据库链接

UniGene:

Gga.2272

SMR:

Q5ZIY4

STRING:

9031.ENSGALP00000001656

KEGG:

gga:417477

Pfam:

PF01172

Uniprot: