Sbds (基因名), Ribosome maturation protein SBDS (蛋白名), sbds_mouse.
产品名称:
Mouse Sbds/ Ribosome maturation protein SBDS CLIA Kit
货号:
U14247m
商标:
EIAab®
监管等级:
别名:
Protein 22A3, Shwachman-Bodian-Diamond syndrome protein homolog
检测方法:
CLIA
特异性:
Natural and recombinant mouse Ribosome maturation protein SBDS
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
Epigenetics
通用注释
亚单元:
Associates with the 60S ribosomal subunit. Interacts with NPM1, RPA1 and PRKDC. May interact with NIP7. Found in a complex consisting of the 60S ribosomal subunit, SBDS and EFL1.
功能:
Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.
亚细胞位置:
Cytoplasm
Nucleus
Nucleolus
Nucleus
Nucleoplasm
Cytoplasm
Cytoskeleton
Spindle
Detected in the cytoplasm, but not in the nucleus (PubMed:21536732). Primarily detected in the cytoplasm, and at low levels in nucleus (PubMed:19602484). Detected in the nucleolus during G1 and G2 phase of the cell cycle, and diffusely distributed in the nucleus during S phase. Detected at the mitotic spindle. Colocalizes with the microtubule organizing center during interphase (By similarity).
该产品尚未在任何出版物中被引用。
反馈墙
评论数 : 0
所有用户
所有用户
默认排序
默认排序
最近
早期
目前还没有评论。
通知
规格
数量
单价 (¥)
小计 1 (¥)
小计 2:
¥
规格
数量
单价 (¥)