Bovine AANAT/ Serotonin N-acetyltransferase CLIA Kit
5-羟色胺-N-乙酰基转移

货号:

U1937b

商标:

EIAab^®

监管等级:

RUO

别名:

Aralkylamine N-acetyltransferase, AA-NAT, Serotonin acetylase, SNAT

检测方法:

CLIA

特异性:

Natural and recombinant bovine Serotonin N-acetyltransferase

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Neurosciences

规格 & 价格:

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通用注释

亚单元:

Monomer (By similarity). Interacts with several 14-3-3 proteins, including YWHAB, YWHAE, YWHAG and YWHAZ, preferentially when phosphorylated at Thr-31 (By similarity). Phosphorylation on Ser-205 also allows binding to YWHAZ, but with lower affinity (By similarity). The interaction with YWHAZ considerably increases affinity for arylalkylamines and acetyl-CoA and protects the enzyme from dephosphorylation and proteasomal degradation. It may also prevent thiol-dependent inactivation.

功能:

Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.

亚细胞位置:

Cytoplasm

数据库链接

UniGene:

Bt.13120

SMR:

O02785

STRING:

9913.ENSBTAP00000019543

KEGG:

bta:281583

Pfam: