Bovine ACAA2/ 3-ketoacyl-CoA thiolase, mitochondrial CLIA Kit

货号:

U16216b

商标:

EIAab^®

监管等级:

RUO

别名:

Acetyl-CoA acetyltransferase, Acetyl-CoA acyltransferase, Acyl-CoA hydrolase, mitochondrial, Beta-ketothiolase, Mitochondrial 3-oxoacyl-CoA thiolase

检测方法:

CLIA

特异性:

Natural and recombinant bovine 3-ketoacyl-CoA thiolase, mitochondrial

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Bovine ACAA2 CLIA Kit

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通用注释

亚单元:

Homotetramer. Interacts with BNIP3.

功能:

In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. Also displays hydrolase activity on various fatty acyl-CoAs (By similarity). Thereby, could be responsible for the production of acetate in a side reaction to beta-oxidation (By similarity). Abolishes BNIP3-mediated apoptosis and mitochondrial damage (By similarity).

亚细胞位置:

Mitochondrion

数据库链接

UniGene:

Bt.48847

SMR:

Q3T0R7

STRING:

9913.ENSBTAP00000003716

KEGG:

bta:522006

Pfam: