Ubr4 (基因名), E3 ubiquitin-protein ligase UBR4 (蛋白名), ubr4_mouse.
产品名称:
Mouse Ubr4/ E3 ubiquitin-protein ligase UBR4 CLIA Kit
E3泛素连接酶UBR4
货号:
U0192m
商标:
EIAab®
监管等级:
别名:
N-recognin-4, RING-type E3 ubiquitin transferase UBR4, Zinc finger UBR1-type protein 1, p600, Kiaa0462, Zubr1
检测方法:
CLIA
特异性:
Natural and recombinant mouse E3 ubiquitin-protein ligase UBR4
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with RB1 and calmodulin.
功能:
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation.
亚细胞位置:
Membrane
Multi-pass membrane protein
Cytoplasm
Cytoplasm
Cytoskeleton
Nucleus
Concentrates at the leading edge of membrane structures involved in actin motility.
数据库链接
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