UFL1 (基因名), E3 UFM1-protein ligase 1 (蛋白名), ufl1_bovin.
产品名称:
Bovine UFL1/ E3 UFM1-protein ligase 1 CLIA Kit
货号:
U4457b
商标:
EIAab®
监管等级:
别名:
E3 UFM1-protein transferase 1, Multiple alpha-helix protein located at ER, Regulator of C53/LZAP and DDRGK1, MAXER, RCAD
检测方法:
CLIA
特异性:
Natural and recombinant bovine E3 UFM1-protein ligase 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
亚单元:
Interacts with DDRGK1. Interacts with UFC1. Interacts with RELA. Interacts with TRIP4. Interacts with CDK5RAP3; the interaction is direct.
功能:
E3 protein ligase that mediates ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, a post-translational modification on lysine residues of proteins that may play a crucial role in a number of cellular processes. Mediates DDRGK1 ufmylation and may regulate the proteasomal degradation of DDRGK1 and CDK5RAP3 thereby modulating NF-kappa-B signaling. May also play a role in nuclear receptor-mediated transcription through TRIP4 ufmylation. May play a role in the unfolded protein response, mediating the ufmylation of multiple proteins in response to endoplasmic reticulum stress. Anchors CDK5RAP3 in the cytoplasm, preventing its translocation to the nucleus which allows expression of the CCND1 cyclin and progression of cells through the G1/S transition.
亚细胞位置:
Endoplasmic reticulum
Cytoplasm
Cytosol
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
该产品尚未在任何出版物中被引用。
反馈墙
评论数 : 0
所有用户
所有用户
默认排序
默认排序
最近
早期
目前还没有评论。
通知
规格
数量
单价 (¥)
小计 1 (¥)
小计 2:
¥
规格
数量
单价 (¥)