Zeb1 (基因名), Zinc finger E-box-binding homeobox 1 (蛋白名), zeb1_mouse.
产品名称:
Mouse Zeb1/ Zinc finger E-box-binding homeobox 1 CLIA Kit
ZEB1
货号:
U14970m
商标:
EIAab®
监管等级:
别名:
Delta EF1, Transcription factor 8, Zinc finger homeobox protein 1a, TCF-8, MEB1, Tcf8, Zfhx1a, Zfx1a, Zfx1ha
检测方法:
CLIA
特异性:
Natural and recombinant mouse Zinc finger E-box-binding homeobox 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
亚单元:
Interacts (via N-terminus) with SMARCA4/BRG1.
功能:
Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1 (By similarity). Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
亚细胞位置:
Nucleus
数据库链接
验证序列:
该产品尚未在任何出版物中被引用。
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