Zeb1 (基因名), Zinc finger E-box-binding homeobox 1 (蛋白名), zeb1_rat.
产品名称:
Rat Zeb1/ Zinc finger E-box-binding homeobox 1 CLIA Kit
ZEB1
货号:
U14970r
商标:
EIAab®
监管等级:
别名:
Transcription factor 8, Zinc finger homeodomain enhancer-binding protein, TCF-8, Zfhep, Tcf8
检测方法:
CLIA
实验类型:
Sandwich
特异性:
Natural and recombinant rat Zinc finger E-box-binding homeobox 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
亚单元:
Interacts (via N-terminus) with SMARCA4/BRG1.
功能:
Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
亚细胞位置:
Nucleus
数据库链接
验证序列:
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